Neurological & CNS Cancers

domain

Cancers of the brain, spinal cord, and nervous system, including gliomas, medulloblastoma, and CNS lymphoma.

107

Centers

7,974

Active Trials

1,876

NIH Grants

$26.5B

NCI Funding

General Cancer Types(263)

NameCenters
Glioblastoma101
Glioma96
NEUROBLASTOMA86
Metastatic Malignant Neoplasm in the Brain82
Medulloblastoma79
MALIGNANT GLIOMA73
Paraganglioma66
Anaplastic Astrocytoma65
Central Nervous System Neoplasm63
Ependymoma63
Low Grade Glioma63
Ganglioneuroblastoma62
Recurrent Malignant Glioma56
Adult Glioblastoma54
Refractory Malignant Glioma53
Brain Ependymoma50
Recurrent Primary Malignant Central Nervous System Neoplasm50
Diffuse Intrinsic Pontine Glioma44
Brain Stem Glioma40
Stage 2 Neuroblastoma38
Cerebral Astrocytoma37
Diffuse Glioma36
Oligodendroglioma36
Glioblastoma, IDH-Wildtype34
Astrocytoma29
Anaplastic Oligodendroglioma28
Astrocytoma, IDH-Mutant, Grade 326
MGMT-Methylated Glioblastoma23
HGG22
Malignant Brain Tumors19
Recurrent GBM18
Brain Neoplasm17
Cerebral Vein Thrombosis17
Meningioma17
Diffuse Midline Glioma16
Glioblastoma Multiforme (GBM)16
Adult Meningioma13
Advanced Paraganglioma13
Diffuse Midline Glioma, H3 K27M-Mutant12
Diffuse Midline Glioma, H3 K27-Altered11
Diffuse Midline Glioma (DMG)9
Intracranial Tumors9
Brain Lesions8
Central Nervous System Embryonal Tumor, Not Otherwise Specified8
Central Nervous System Ganglioneuroblastoma8
Mixed Glioma8
Primary Central Nervous System Neoplasm8
Brain Stem Neoplasm7
High Grade Gliomas7
Low-Grade Gliomas7
Craniopharyngioma5
Grade IV Glioma5
Malignant Brain Neoplasm5
Primary Malignant Brain Tumors5
Adult Brain Tumors4
Astrocytoma, IDH-Mutant4
Brain Necrosis4
Cerebral Edema4
CNS Disease4
Melanoma Brain Metastasis4
Refractory Brain Neoplasm4
Anaplastic (Malignant) Meningioma3
Atypical Meningioma3
Brain Glioblastoma3
Brain Irradiation3
Central Nervous System (CNS) Metastases3
Central Nervous System Cancer3
CNS Malignancies3
H3K27-altered High Grade Glioma3
Intracranial Neoplasm3
Meningiomas3
Optic Pathway Glioma3
Optic Pathway Gliomas3
Progressive DIPG3
Recurrent Brain Metastases3
Recurrent DIPG3
Refractory DIPG3
Supratentorial Meningioma3
Adult Central Nervous System Germ Cell Tumor2
Advanced Non-Central Nervous System (CNS) Malignancies2
Anaplastic Astrocytoma (AA)2
Anaplastic Oligodendroglioma (AO)2
Arteriovenous Malformation of Central Nervous System2
Basal Ganglia Glioma2
Brain and Nervous System2
Brain Neoplasms, Benign2
Brain Tumor, DIPG2
Brain Tumor, Refractory2
Central Nervous System Vasculitis2
Glioblastoma Multiforme of Brain2
H3 K27M Glioma2
Hereditary Paraganglioma2
Hereditary Paraganglioma-Pheochromocytoma Syndrome2
IDH1 Mutated or MGMT Methylated Recurrent HGG (Not Recruiting)2
Infratentorial Glioma2
Intracranial Glioma2
Malignant Central Nervous System Neoplasm2
Malignant Neoplasms, Brain2
Multiple Brain Metastases2
Primary Central Nervous System Carcinoma2
Primary Malignant Brain Neoplasms2
Primary Refractory Neuroblastoma2
Progressive Brain Metastases2
Recurrent Astrocytoma2
Secondary Malignant Neoplasm of Brain and Cerebral Meninges2
Spinal Cord Compression2
Spinal Metastases2
Stage III Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity2
Thalamic Glioma2
WHO Grade III or IV Recurrent Glioma2
Abdominal Neuroblastoma1
Advanced Metastatic Paraganglioma1
Anaplastic Astrocytoma of Brain1
Anaplastic Glioma1
Anaplastic Meningioma1
Anaplastic Mixed Gliomas1
Anaplastic Oligo-astrocytoma (AOA)1
Atypical/Malignant Meningioma1
Benign Neoplasms, Brain1
Brain Cancer Metastatic1
Brain Lesion1
Brain Metastases From Extra-cranial Solid Tumors1
Brain Neoplasm, Primary1
Brain Tumor Adult1
Brain Tumor, Recurrent, Adult1
Brain Tumors and/or Solid Tumors Including1
Cancer (High-grace Glioma)1
Cancer (With CNS Involvement)1
Central Nervous System Disorder1
Central Nervous System Germ Cell Tumor1
Central Nervous System Malignancies1
Central Nervous System/Leptomeningeal Neoplasms1
CNS1
CNS BRAIN1
CNS Brain Cancer1
CNS Embryonal Tumor With Rhabdoid Features1
CNS Malignancy1
CNS Neoplasm1
CNS-Spinal CD/MEMBR, NOS1
Diffuse Astrocytoma, IDH-Wildtype (Grade 2-4)1
DIPG Brain Tumor1
Embryonal Tumor of CNS1
Familial Neuroblastoma1
Ganglioneuroblastoma of Central Nervous System1
Glial Tumor of Brain1
Glioblastoma or Gliosarcoma1
Glioblastoma or Malignant Glioma1
Glioblastoma Surgery1
Glioblastoma With Primitive Neuronal Component1
Glioblastoma, IDH-mutant1
Glioma of Spinal Cord1
Glioma, Diffuse Midline, H3K27M-mutant1
Glioma, High Grade1
Glioma, Recurrent High Grade1
Glioma, Recurrent Malignant1
Gliosarcoma of Brain1
Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma1
Grade 3 or 4 Astrocytoma1
Grade I Meningioma1
High Grade CNS Tumors1
High Grade Glioma: Glioblastoma (GBM)1
High Grade Glioma: Gliosarcoma1
High Grade Meningioma1
IDH Wildtype Glioblastoma1
IDH Wildtype Recurrent Glioblastoma1
INI1 (SMARCB1)-Deficient Primary CNS Malignant Tumors1
Intracranial Neoplasms1
Low Grade CNS Tumors1
Malignant Brain Glioma1
Malignant Glioma NOS1
Malignant Neoplasm, Brain1
Malignant Paraganglioma1
Metastases, CNS1
Metastasis to Brain1
Metastatic Neuroblastoma1
Metastatic Spinal Lesions1
Mixed Anaplastic Oligoastrocytoma (AOA)1
Neoplasms, Brain1
Neoplasms, Intracranial1
Neuroblastoma (NB)1
Neuroblastoma. CNS1
Newly Diagnosed Astrocytoma, Grade IV1
Pilomyxoid Astrocytoma1
Pleomorphic Xantho-Astrocytoma1
Pleomorphic Xanthoastrocytoma, Anaplastic1
Primary Brain Neoplasm1
Primary Brain Neoplasms1
Primary Glioblastoma1
Primary or Metastatic Central Nervous System (CNS) Tumor1
Progressive Low-Grade Glioma1
Progressive or Refractory High-Grade Glioma1
Rare CNS Tumor Recurrent1
Recurrent Astrocytoma, Grade IV1
Recurrent Central Nervous System Neoplasm1
Recurrent Glioblastoma Multiforme (GBM)1
Recurrent Low-Grade Glioma1
Recurrent Malignant Gliomas1
Recurrent Oligodendroglioma1
Recurrent Paraganglioma1
Recurrent Supratentorial Glioblastoma1
Refractory Brain Tumor1
Refractory Glioblastoma1
Relapsed/Recurrent GBM (Phase 2)1
Resectable Astrocytoma1
Resectable Glioblastoma1
SMARCA4-deficient Primary CNS Malignant Tumors1
Solid Tumor (Excluding CNS)1
Solid Tumors, Glioblastoma, Recurrent Malignant Gliomas1
Solid, Liquid, Central Nervous System Tumors1
Spinal Surgery1
Stage III and IV Glioma Patients1
Stage IVA Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity1
Stage IVB Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity1
Stage IVC Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity1
Supratentorial Ependymoma1
Suspected Central Nervous System Tumors1
Whole Brain Radiation1
Adult Benign Brain Neoplasm—
Adult Brain Neoplasm—
Adult Brain Stem Neoplasm—
Adult Central Nervous System Embryonal Tumor, Not Otherwise Specified—
Adult Central Nervous System Neoplasm—
Adult Diffuse Hemispheric Glioma, H3 G34-Mutant—
Adult Diffuse Midline Glioma, H3 K27-Mutant—
Adult Grade 3 Meningioma—
Adult Intracranial Neoplasm—
Adult Malignant Brain Neoplasm—
Astrocytoma, IDH-Wildtype—
Benign Central Nervous System Mesenchymal, Non-Meningothelial Neoplasm—
Benign Spinal Cord Neoplasm—
Brain Astrocytoma—
Brain Disorder—
Brain Embryonal Tumor, Not Otherwise Specified—
Brain Germinoma—
Brain Low Grade Glioma—
Central Nervous System Choriocarcinoma—
Central Nervous System Degenerative Disorder—
Central Nervous System Embryonal Tumor—
Central Nervous System Hemangioblastoma—
Central Nervous System Hematopoietic and Lymphoid Cell Neoplasm—
Central Nervous System Mixed Germ Cell Tumor—
Central Nervous System Part—
Central Nervous System Teratoma—
Central Nervous System Yolk Sac Tumor—
Cerebellar Astrocytoma—
Infratentorial Glioblastoma—
Intraspinal Neoplasm—
Locally Advanced Glioma—
Malignant Brain Stem Neoplasm—
Medulloblastoma Molecular Subtypes—
Metastatic Carcinoma in the Central Nervous System—
Mixed Mouse Gliomas—
Mouse Craniopharyngioma—
Mouse Diffuse Astrocytoma—
Mouse Ependymoma—
NCI CTEP SDC CNS Neoplasm (Primary Tumor) Category Terminology—
Non-Neoplastic Central Nervous System Disorder—
Retinal Astrocytoma—
Spinal Cord Neoplasm—
Spinal Neoplasm—
Untreated Central Nervous System Neoplasm—
White Matter of the Spinal Cord—
WHO Grade 1 Glioma—

Top Centers for Neurological & CNS Cancers(107)

Ranked by research excellence score (trials · grants · publications). Methodology →

#CenterScore
1
Holden Comprehensive Cancer CenterIowa City, IA
NCI Comprehensive
—
2
Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA
NCI Comprehensive
—
3
Livestrong Cancer InstitutesAustin, TX
—
4
Upstate Cancer CenterSyracuse, NY
—
5
Dana-Farber Cancer InstituteBoston, MA
NCI Comprehensive
—
6
Comprehensive Cancer Center St. Jude Children’s Research HospitalMemphis, TN
NCI Comprehensive
—
7
Case Comprehensive Cancer CenterCleveland, OH
NCI Comprehensive
—
8
Sylvester Comprehensive Cancer CenterMiami, FL
NCI Clinical
—
9
Cleveland Clinic Cancer CenterCleveland, OH
—
10
UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR
—
11
Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX
—
12
Penn State Cancer InstituteHershey, PA
—
13
University of Cincinnati Cancer CenterCincinnati, OH
—
14
The University of Vermont Cancer CenterBurlington, VT
—
15
University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR
—
16
Northwell Health Cancer InstituteNew York, NY
—
17
Loma Linda University Cancer CenterLoma Linda, CA
—
18
Tampa General Hospital Cancer InstituteTampa, FL
—
19
Memorial Sloan Kettering Cancer CenterNew York, NY
NCI Comprehensive
—
20
UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, CA
NCI Comprehensive
—
21
Fred Hutch Cancer CenterSeattle, WA
NCI Comprehensive
—
22
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD
NCI Comprehensive
—
23
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA
NCI Comprehensive
—
24
University of Michigan Rogel Cancer CenterAnn Arbor, MI
NCI Comprehensive
—
25
Stanford Cancer InstitutePalo Alto, CA
NCI Comprehensive
—
26
Siteman Cancer CenterSt. Louis, MO
NCI Comprehensive
—
27
UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC
NCI Comprehensive
—
28
UPMC Hillman Cancer CenterPittsburgh, PA
NCI Comprehensive
—
29
Mayo Clinic Comprehensive Cancer CenterRochester, MN
NCI Comprehensive
—
30
Yale Cancer Center Yale School of MedicineNew Haven, CT
NCI Comprehensive
—
31
Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicago, IL
NCI Comprehensive
—
32
Vanderbilt-Ingram Cancer CenterNashville, TN
NCI Comprehensive
—
33
Herbert Irving Comprehensive Cancer CenterNew York, NY
NCI Comprehensive
—
34
UC San Diego Moores Cancer CenterLa Jolla, CA
NCI Comprehensive
—
35
Mount Sinai Tisch Cancer CenterNew York, NY
NCI Comprehensive
—
36
Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX
NCI Comprehensive
—
37
The University of Texas MD Anderson Cancer CenterHouston, TX
NCI Comprehensive
—
38
UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
—
39
Duke Cancer InstituteDurham, NC
NCI Comprehensive
—
40
The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL
NCI Comprehensive
—
41
Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX
NCI Comprehensive
—
42
Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY
NCI Comprehensive
—
43
Sandra and Edward Meyer Cancer Center at Weill Cornell MedicineNew York, NY
—
44
Winship Cancer InstituteAtlanta, GA
NCI Comprehensive
—
45
The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH
NCI Comprehensive
—
46
Masonic Cancer CenterMinneapolis, MN
NCI Comprehensive
—
47
University of Wisconsin Carbone Cancer CenterMadison, WI
NCI Comprehensive
—
48
OHSU Knight Cancer InstitutePortland, OR
NCI Comprehensive
—
49
City of Hope Comprehensive Cancer CenterDuarte, CA
NCI Comprehensive
—
50
USC Norris Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
—
51
University of Colorado Cancer CenterAurora, CO
NCI Comprehensive
—
52
Moffitt Cancer CenterTampa, FL
NCI Comprehensive
—
53
O’Neal Comprehensive Cancer Center at the University of Alabama at BirminghamBirmingham, AL
NCI Comprehensive
—
54
Huntsman Cancer Institute at the University of UtahSalt Lake City, UT
NCI Comprehensive
—
55
UF Health Cancer InstituteGainesville, FL
NCI Clinical
—
56
Montefiore Einstein Comprehensive Cancer CenterBronx, NY
NCI Comprehensive
—
57
UC Davis Comprehensive Cancer CenterSacramento, CA
NCI Comprehensive
—
58
Roswell Park Comprehensive Cancer CenterBuffalo, NY
NCI Comprehensive
—
59
University of Virginia Cancer CenterCharlottesville, VA
NCI Comprehensive
—
60
Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN
NCI Comprehensive
—
61
Hollings Cancer CenterCharleston, SC
NCI Clinical
—
62
The University of Arizona Cancer CenterTucson, AZ
NCI Comprehensive
—
63
UCI Chao Family Comprehensive Cancer CenterOrange, CA
NCI Comprehensive
—
64
Medical College of Wisconsin Cancer CenterMilwaukee, WI
—
65
Cedars-Sinai CancerLos Angeles, CA
—
66
VCU Massey Comprehensive Cancer CenterRichmond, VA
NCI Comprehensive
—
67
UK Markey Cancer CenterLexington, KY
NCI Comprehensive
—
68
UMass Memorial Health Cancer CenterWorcester, MA
—
69
Wilmot Cancer Institute, UR MedicineRochester, NY
NCI Clinical
—
70
Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC
NCI Comprehensive
—
71
Georgetown Lombardi Comprehensive Cancer CenterWashington, DC
NCI Comprehensive
—
72
Koch Institute for Integrative Cancer Research at MITCambridge, MA
NCI Basic_laboratory
—
73
Fred & Pamela Buffett Cancer CenterOmaha, NE
NCI Clinical
—
74
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer CenterBaltimore, MD
NCI Comprehensive
—
75
The University of Kansas Cancer CenterKansas City, KS
NCI Comprehensive
—
76
Ellen and Ronald Caplan Cancer Center of The Wistar InstitutePhiladelphia, PA
NCI Basic_laboratory
—
77
Dartmouth Cancer CenterLebanon, NH
NCI Comprehensive
—
78
Stephenson Cancer CenterOklahoma City, OK
NCI Clinical
—
79
Rutgers Cancer InstituteNew Brunswick, NJ
NCI Comprehensive
—
80
University of Illinois Cancer CenterChicago, IL
—
81
University of Hawai‘i Cancer CenterHonolulu, HI
NCI Clinical
—
82
GW Cancer CenterWashington, DC
—
83
Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA
NCI Basic_laboratory
—
84
University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM
NCI Comprehensive
—
85
Cold Spring Harbor Laboratory Cancer CenterCold Spring Harbor, NY
NCI Basic_laboratory
—
86
Fox Chase Cancer CenterPhiladelphia, PA
NCI Comprehensive
—
87
Salk Institute Cancer CenterLa Jolla, CA
NCI Basic_laboratory
—
88
Boston University Cancer CenterBoston, MA
—
89
Karmanos Cancer InstituteDetroit, MI
NCI Comprehensive
—
90
Purdue University Institute for Cancer ResearchWest Lafayette, IN
NCI Basic_laboratory
—
91
Cancer Center at IllinoisUrbana, IL
—
92
Stony Brook Cancer CenterStony Brook, NY
—
93
The Jackson Laboratory Cancer CenterBar Harbor, ME
NCI Basic_laboratory
—
94
Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL
—
95
UofL James Graham Brown Cancer CenterLouisville, KY
—
96
Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ
—
97
Georgia Cancer Center, Augusta UniversityAugusta, GA
—
98
LSU LCMC Health Cancer CenterNew Orleans, LA
—
99
Ellis Fischel Cancer Center, MU Health CareColumbia, MO
—
100
Legorreta Cancer Center at Brown UniversityProvidence, RI
—
101
WVU Cancer InstituteMorgantown, WV
—
102
Cardinal Bernardin Cancer CenterMaywood, IL
—
103
University of Texas Medical Branch Cancer CenterGalveston, TX
—
104
Princess Margaret Cancer CentreToronto, ON
—
105
Murtha Cancer Center at Walter Reed BethesdaBethesda, MD
—
106
BC CancerVancouver, BC
—
107
Louisiana Cancer Research CenterNew Orleans, LA
—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →