Mantle Cell Lymphoma

general

A non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.

91

Centers

317

Active Trials

$1.3B

Cancer Funding

Specific Cancer Types(6)

NameCenters
Recurrent Mantle Cell Lymphoma48
Refractory Mantle Cell Lymphoma27
Mantle Cell Lymphoma; Non-Hodgkin Lymphoma6
Blastoid Variant Mantle Cell Lymphoma4
Mantle Cell Lymphoma Refractory4
Prostate Mantle Cell Lymphoma—

Top Centers for Mantle Cell Lymphoma(91)

Ranked by research excellence score (trials · grants · publications). Methodology →

#CenterScore
1
The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH
NCI Comprehensive
High-Volume Research Center
90.2
2
The University of Texas MD Anderson Cancer CenterHouston, TX
NCI Comprehensive
High-Volume Research Center
85.6
3
City of Hope Comprehensive Cancer CenterDuarte, CA
NCI Comprehensive
High-Volume Research Center
85.0
4
Fred & Pamela Buffett Cancer CenterOmaha, NE
NCI Clinical
High-Volume Research Center
77.3
5
Moffitt Cancer CenterTampa, FL
NCI Comprehensive
High-Volume Research Center
76.1
6
Sylvester Comprehensive Cancer CenterMiami, FL
NCI Clinical
High-Volume Research Center
75.4
7
Stanford Cancer InstitutePalo Alto, CA
NCI Comprehensive
High-Volume Research Center
74.2
8
Fred Hutch Cancer CenterSeattle, WA
NCI Comprehensive
High-Volume Research Center
73.7
9
Dana-Farber Cancer InstituteBoston, MA
NCI Comprehensive
High-Volume Research Center
73.4
10
Huntsman Cancer Institute at the University of UtahSalt Lake City, UT
NCI Comprehensive
High-Volume Research Center
71.8
11
University of Colorado Cancer CenterAurora, CO
NCI Comprehensive
High-Volume Research Center
70.7
12
The University of Kansas Cancer CenterKansas City, KS
NCI Comprehensive
High-Volume Research Center
70.7
13
Siteman Cancer CenterSt. Louis, MO
NCI Comprehensive
High-Volume Research Center
70.0
14
Karmanos Cancer InstituteDetroit, MI
NCI Comprehensive
Active Research Program
69.2
15
Medical College of Wisconsin Cancer CenterMilwaukee, WI
Active Research Program
68.9
16
Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ
Active Research Program
68.1
17
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA
NCI Comprehensive
Active Research Program
67.8
18
Yale Cancer Center Yale School of MedicineNew Haven, CT
NCI Comprehensive
Active Research Program
67.5
19
Roswell Park Comprehensive Cancer CenterBuffalo, NY
NCI Comprehensive
Active Research Program
67.2
20
Winship Cancer InstituteAtlanta, GA
NCI Comprehensive
Active Research Program
65.9
21
University of Virginia Cancer CenterCharlottesville, VA
NCI Comprehensive
Active Research Program
65.2
22
The University of Arizona Cancer CenterTucson, AZ
NCI Comprehensive
Active Research Program
64.1
23
Memorial Sloan Kettering Cancer CenterNew York, NY
NCI Comprehensive
Active Research Program
64.0
24
University of Illinois Cancer CenterChicago, IL
Active Research Program
63.1
25
University of Wisconsin Carbone Cancer CenterMadison, WI
NCI Comprehensive
Active Research Program
62.0
26
Duke Cancer InstituteDurham, NC
NCI Comprehensive
Active Research Program
61.9
27
Boston University Cancer CenterBoston, MA
Active Research Program
61.6
28
Princess Margaret Cancer CentreToronto, ON
Active Research Program
61.2
29
Dartmouth Cancer CenterLebanon, NH
NCI Comprehensive
Active Research Program
60.1
30
Mayo Clinic Comprehensive Cancer CenterRochester, MN
NCI Comprehensive
Active Research Program
59.5
31
The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL
NCI Comprehensive
Active Research Program
59.4
32
UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC
NCI Comprehensive
Active Research Program
57.1
33
Cancer Center at IllinoisUrbana, IL
Active Research Program
56.7
34
BC CancerVancouver, BC
Active Research Program
56.0
35
Vanderbilt-Ingram Cancer CenterNashville, TN
NCI Comprehensive
Active Research Program
55.3
36
Masonic Cancer CenterMinneapolis, MN
NCI Comprehensive
Active Research Program
53.9
37
Herbert Irving Comprehensive Cancer CenterNew York, NY
NCI Comprehensive
Active Research Program
53.5
38
Cleveland Clinic Cancer CenterCleveland, OH
Active Research Program
53.4
39
Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL
Active Research Program
53.4
40
Case Comprehensive Cancer CenterCleveland, OH
NCI Comprehensive
Active Research Program
52.8
41
University of Michigan Rogel Cancer CenterAnn Arbor, MI
NCI Comprehensive
Active Research Program
52.4
42
UPMC Hillman Cancer CenterPittsburgh, PA
NCI Comprehensive
Active Research Program
52.0
43
Wilmot Cancer Institute, UR MedicineRochester, NY
NCI Clinical
Active Research Program
51.1
44
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer CenterBaltimore, MD
NCI Comprehensive
Active Research Program
51.0
45
University of Cincinnati Cancer CenterCincinnati, OH
Active Research Program
50.5
46
Louisiana Cancer Research CenterNew Orleans, LA
Active Research Program
49.8
47
Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC
NCI Comprehensive
Active Research Program
47.8
48
Georgia Cancer Center, Augusta UniversityAugusta, GA
Active Research Program
47.0
49
UF Health Cancer InstituteGainesville, FL
NCI Clinical
Active Research Program
46.7
50
Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX
NCI Comprehensive
Active Research Program
45.6
51
Fox Chase Cancer CenterPhiladelphia, PA
NCI Comprehensive
Active Research Program
45.3
52
GW Cancer CenterWashington, DC
Active Research Program
44.9
53
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD
NCI Comprehensive
Active Research Program
44.3
54
OHSU Knight Cancer InstitutePortland, OR
NCI Comprehensive
Active Research Program
43.6
55
Montefiore Einstein Comprehensive Cancer CenterBronx, NY
NCI Comprehensive
Active Research Program
43.5
56
The University of Vermont Cancer CenterBurlington, VT
Active Research Program
42.4
57
University of Texas Medical Branch Cancer CenterGalveston, TX
Active Research Program
42.4
58
Sandra and Edward Meyer Cancer Center at Weill Cornell MedicineNew York, NY
Active Research Program
42.2
59
UC San Diego Moores Cancer CenterLa Jolla, CA
NCI Comprehensive
Active Research Program
41.7
60
VCU Massey Comprehensive Cancer CenterRichmond, VA
NCI Comprehensive
Active Research Program
40.0
61
USC Norris Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
Active Research Program
38.0
62
Northwell Health Cancer InstituteNew York, NY
Active Research Program
37.2
63
Hollings Cancer CenterCharleston, SC
NCI Clinical
Active Research Program
36.4
64
UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, CA
NCI Comprehensive
Active Research Program
36.3
65
Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY
NCI Comprehensive
Active Research Program
36.0
66
Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN
NCI Comprehensive
Active Research Program
36.0
67
Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA
NCI Comprehensive
Active Research Program
36.0
68
Rutgers Cancer InstituteNew Brunswick, NJ
NCI Comprehensive
Active Research Program
36.0
69
UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR
Active Research Program
36.0
70
University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR
Active Research Program
36.0
71
Tampa General Hospital Cancer InstituteTampa, FL
Active Research Program
36.0
72
Georgetown Lombardi Comprehensive Cancer CenterWashington, DC
NCI Comprehensive
Active Research Program
35.1
73
UC Davis Comprehensive Cancer CenterSacramento, CA
NCI Comprehensive
Contributing Research Center
34.2
74
Holden Comprehensive Cancer CenterIowa City, IA
NCI Comprehensive
Contributing Research Center
33.5
75
UofL James Graham Brown Cancer CenterLouisville, KY
Contributing Research Center
33.3
76
Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX
Contributing Research Center
32.8
77
Cedars-Sinai CancerLos Angeles, CA
Contributing Research Center
28.6
78
UMass Memorial Health Cancer CenterWorcester, MA
Contributing Research Center
28.6
79
University of Hawai‘i Cancer CenterHonolulu, HI
NCI Clinical
Contributing Research Center
28.6
80
Penn State Cancer InstituteHershey, PA
Contributing Research Center
28.6
81
The Jackson Laboratory Cancer CenterBar Harbor, ME
NCI Basic_laboratory
Contributing Research Center
28.6
82
Upstate Cancer CenterSyracuse, NY
Contributing Research Center
28.6
83
Livestrong Cancer InstitutesAustin, TX
Contributing Research Center
26.9
84
Stephenson Cancer CenterOklahoma City, OK
NCI Clinical
Contributing Research Center
25.8
85
Loma Linda University Cancer CenterLoma Linda, CA
Contributing Research Center
24.2
86
University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM
NCI Comprehensive
Contributing Research Center
24.0
87
Stony Brook Cancer CenterStony Brook, NY
20.7
88
Cardinal Bernardin Cancer CenterMaywood, IL
20.7
89
UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
—
90
Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX
NCI Comprehensive
—
91
Comprehensive Cancer Center St. Jude Children’s Research HospitalMemphis, TN
NCI Comprehensive
—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →