Diffuse Large B Cell Lymphoma

general

A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous dif

95

Centers

639

Active Trials

$1.1B

Cancer Funding

Specific Cancer Types(12)

NameCenters
EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified55
Large B-cell Lymphoma52
Double Expressor Lymphoma48
Primary Effusion Lymphoma39
Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation36
HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified36
Intravascular Large B-Cell Lymphoma36
High Grade B-cell Lymphoma (HGBCL)30
T-Cell/Histiocyte-Rich Large B-Cell Lymphoma29
Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)28
ALK-Positive Large B-Cell Lymphoma20
EBV-Positive DLBCL, NOS15

Top Centers for Diffuse Large B Cell Lymphoma(95)

Ranked by research excellence score (trials · grants · publications). Methodology →

#CenterScore
1
Memorial Sloan Kettering Cancer CenterNew York, NY
NCI Comprehensive
High-Volume Research Center
91.9
2
Dana-Farber Cancer InstituteBoston, MA
NCI Comprehensive
High-Volume Research Center
88.7
3
University of Colorado Cancer CenterAurora, CO
NCI Comprehensive
High-Volume Research Center
87.8
4
The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL
NCI Comprehensive
High-Volume Research Center
82.5
5
The University of Texas MD Anderson Cancer CenterHouston, TX
NCI Comprehensive
High-Volume Research Center
79.9
6
The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH
NCI Comprehensive
High-Volume Research Center
78.4
7
Siteman Cancer CenterSt. Louis, MO
NCI Comprehensive
High-Volume Research Center
78.0
8
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA
NCI Comprehensive
High-Volume Research Center
77.1
9
Stanford Cancer InstitutePalo Alto, CA
NCI Comprehensive
High-Volume Research Center
74.0
10
Duke Cancer InstituteDurham, NC
NCI Comprehensive
High-Volume Research Center
74.0
11
Fred Hutch Cancer CenterSeattle, WA
NCI Comprehensive
High-Volume Research Center
73.2
12
Sylvester Comprehensive Cancer CenterMiami, FL
NCI Clinical
High-Volume Research Center
72.8
13
The University of Kansas Cancer CenterKansas City, KS
NCI Comprehensive
High-Volume Research Center
72.0
14
University of Wisconsin Carbone Cancer CenterMadison, WI
NCI Comprehensive
High-Volume Research Center
71.0
15
UPMC Hillman Cancer CenterPittsburgh, PA
NCI Comprehensive
Active Research Program
68.3
16
Karmanos Cancer InstituteDetroit, MI
NCI Comprehensive
Active Research Program
67.6
17
University of Virginia Cancer CenterCharlottesville, VA
NCI Comprehensive
Active Research Program
67.0
18
Fred & Pamela Buffett Cancer CenterOmaha, NE
NCI Clinical
Active Research Program
65.7
19
Mayo Clinic Comprehensive Cancer CenterRochester, MN
NCI Comprehensive
Active Research Program
64.5
20
City of Hope Comprehensive Cancer CenterDuarte, CA
NCI Comprehensive
Active Research Program
64.5
21
Vanderbilt-Ingram Cancer CenterNashville, TN
NCI Comprehensive
Active Research Program
64.4
22
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD
NCI Comprehensive
Active Research Program
63.7
23
Cleveland Clinic Cancer CenterCleveland, OH
Active Research Program
63.6
24
Medical College of Wisconsin Cancer CenterMilwaukee, WI
Active Research Program
63.3
25
Winship Cancer InstituteAtlanta, GA
NCI Comprehensive
Active Research Program
63.2
26
Holden Comprehensive Cancer CenterIowa City, IA
NCI Comprehensive
Active Research Program
62.2
27
Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX
Active Research Program
61.4
28
University of Illinois Cancer CenterChicago, IL
Active Research Program
60.5
29
BC CancerVancouver, BC
Active Research Program
59.3
30
University of Cincinnati Cancer CenterCincinnati, OH
Active Research Program
58.5
31
The University of Arizona Cancer CenterTucson, AZ
NCI Comprehensive
Active Research Program
58.4
32
Boston University Cancer CenterBoston, MA
Active Research Program
57.9
33
Rutgers Cancer InstituteNew Brunswick, NJ
NCI Comprehensive
Active Research Program
57.5
34
Herbert Irving Comprehensive Cancer CenterNew York, NY
NCI Comprehensive
Active Research Program
57.3
35
Wilmot Cancer Institute, UR MedicineRochester, NY
NCI Clinical
Active Research Program
57.1
36
Koch Institute for Integrative Cancer Research at MITCambridge, MA
NCI Basic_laboratory
Active Research Program
56.2
37
Roswell Park Comprehensive Cancer CenterBuffalo, NY
NCI Comprehensive
Active Research Program
55.6
38
Moffitt Cancer CenterTampa, FL
NCI Comprehensive
Active Research Program
55.4
39
Cancer Center at IllinoisUrbana, IL
Active Research Program
54.9
40
Princess Margaret Cancer CentreToronto, ON
Active Research Program
54.7
41
University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM
NCI Comprehensive
Active Research Program
51.2
42
Stephenson Cancer CenterOklahoma City, OK
NCI Clinical
Active Research Program
51.1
43
Northwell Health Cancer InstituteNew York, NY
Active Research Program
50.7
44
Dartmouth Cancer CenterLebanon, NH
NCI Comprehensive
Active Research Program
49.6
45
Case Comprehensive Cancer CenterCleveland, OH
NCI Comprehensive
Active Research Program
49.4
46
Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA
NCI Comprehensive
Active Research Program
49.1
47
University of Michigan Rogel Cancer CenterAnn Arbor, MI
NCI Comprehensive
Active Research Program
49.0
48
UF Health Cancer InstituteGainesville, FL
NCI Clinical
Active Research Program
48.3
49
OHSU Knight Cancer InstitutePortland, OR
NCI Comprehensive
Active Research Program
47.7
50
Louisiana Cancer Research CenterNew Orleans, LA
Active Research Program
47.4
51
UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR
Active Research Program
47.0
52
Georgia Cancer Center, Augusta UniversityAugusta, GA
Active Research Program
46.1
53
Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ
Active Research Program
45.5
54
University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR
Active Research Program
45.2
55
UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC
NCI Comprehensive
Active Research Program
45.0
56
Upstate Cancer CenterSyracuse, NY
Active Research Program
43.9
57
Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC
NCI Comprehensive
Active Research Program
42.8
58
Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY
NCI Comprehensive
Active Research Program
39.8
59
Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicago, IL
NCI Comprehensive
Active Research Program
39.6
60
Penn State Cancer InstituteHershey, PA
Active Research Program
39.4
61
Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL
Active Research Program
39.3
62
University of Texas Medical Branch Cancer CenterGalveston, TX
Active Research Program
39.3
63
Sandra and Edward Meyer Cancer Center at Weill Cornell MedicineNew York, NY
Active Research Program
39.0
64
UCI Chao Family Comprehensive Cancer CenterOrange, CA
NCI Comprehensive
Active Research Program
39.0
65
Fox Chase Cancer CenterPhiladelphia, PA
NCI Comprehensive
Active Research Program
38.5
66
Cedars-Sinai CancerLos Angeles, CA
Active Research Program
37.9
67
UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
Active Research Program
37.6
68
UC San Diego Moores Cancer CenterLa Jolla, CA
NCI Comprehensive
Active Research Program
37.3
69
Tampa General Hospital Cancer InstituteTampa, FL
Active Research Program
36.6
70
Masonic Cancer CenterMinneapolis, MN
NCI Comprehensive
Active Research Program
36.3
71
University of Hawai‘i Cancer CenterHonolulu, HI
NCI Clinical
Active Research Program
35.5
72
Stony Brook Cancer CenterStony Brook, NY
Active Research Program
35.3
73
VCU Massey Comprehensive Cancer CenterRichmond, VA
NCI Comprehensive
Contributing Research Center
34.9
74
Cardinal Bernardin Cancer CenterMaywood, IL
Contributing Research Center
34.3
75
UC Davis Comprehensive Cancer CenterSacramento, CA
NCI Comprehensive
Contributing Research Center
33.0
76
Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN
NCI Comprehensive
Contributing Research Center
32.9
77
The University of Vermont Cancer CenterBurlington, VT
Contributing Research Center
32.9
78
Ellis Fischel Cancer Center, MU Health CareColumbia, MO
Contributing Research Center
31.7
79
Huntsman Cancer Institute at the University of UtahSalt Lake City, UT
NCI Comprehensive
Contributing Research Center
31.3
80
The Jackson Laboratory Cancer CenterBar Harbor, ME
NCI Basic_laboratory
Contributing Research Center
30.6
81
Yale Cancer Center Yale School of MedicineNew Haven, CT
NCI Comprehensive
Contributing Research Center
29.5
82
Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX
NCI Comprehensive
Contributing Research Center
28.2
83
Georgetown Lombardi Comprehensive Cancer CenterWashington, DC
NCI Comprehensive
Contributing Research Center
27.7
84
Loma Linda University Cancer CenterLoma Linda, CA
Contributing Research Center
27.3
85
Hollings Cancer CenterCharleston, SC
NCI Clinical
Contributing Research Center
25.5
86
UMass Memorial Health Cancer CenterWorcester, MA
Contributing Research Center
24.2
87
Salk Institute Cancer CenterLa Jolla, CA
NCI Basic_laboratory
Contributing Research Center
24.2
88
UofL James Graham Brown Cancer CenterLouisville, KY
Contributing Research Center
24.2
89
USC Norris Comprehensive Cancer CenterLos Angeles, CA
NCI Comprehensive
Contributing Research Center
24.0
90
Legorreta Cancer Center at Brown UniversityProvidence, RI
Contributing Research Center
23.6
91
UMMC Cancer Center and Research InstituteJackson, MS
16.3
92
Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX
NCI Comprehensive
—
93
Montefiore Einstein Comprehensive Cancer CenterBronx, NY
NCI Comprehensive
—
94
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer CenterBaltimore, MD
NCI Comprehensive
—
95
Ellen and Ronald Caplan Cancer Center of The Wistar InstitutePhiladelphia, PA
NCI Basic_laboratory
—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →