Laryngeal Squamous Cell Carcinoma

general

A squamous cell carcinoma that arises from the larynx. It is the most common histologic type of laryngeal carcinoma. It can arise from the glottis, supraglottic area, or it can be transglottic. Glottic squamous cell carcinoma is the most frequent laryngeal carcinoma in the United States. The symptoms, clinical behavior and the prognosis depend on the site of origin within the larynx.

Centers

449

Active Trials

$3.8B

Cancer Funding

Specific Cancer Types(9)

Name	Centers	Active Trials
Recurrent Laryngeal Squamous Cell Carcinoma	70	139
Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7	65	72
Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7	53	46
Metastatic Laryngeal Squamous Cell Carcinoma	51	87
Refractory Laryngeal Squamous Cell Carcinoma	20	20
Recurrent Squamous Cell Carcinoma of the Larynx	17	—
Stage IV Squamous Cell Carcinoma of the Larynx	15	—
Unresectable Laryngeal Squamous Cell Carcinoma	5	5
Laryngeal Spindle Cell Squamous Carcinoma	—	—

Top Centers for Laryngeal Squamous Cell Carcinoma(82)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive High-Volume Research Center	High-Volume Research Center	12	—	72.9
2	UPMC Hillman Cancer CenterPittsburgh, PA NCI Comprehensive Active Research Program	Active Research Program	8	—	66.2
3	UC San Diego Moores Cancer CenterLa Jolla, CA NCI Comprehensive Active Research Program	Active Research Program	6	—	66.2
4	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive Active Research Program	Active Research Program	12	—	66.2
5	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	15	—	66.2
6	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	14	—	66.2
7	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	9	—	66.2
8	Moffitt Cancer CenterTampa, FL NCI Comprehensive Active Research Program	Active Research Program	7	—	66.2
9	Montefiore Einstein Comprehensive Cancer CenterBronx, NY NCI Comprehensive Active Research Program	Active Research Program	8	—	66.2
10	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	14	—	66.2
11	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	4	—	66.2
12	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	7	—	66.2
13	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	9	—	66.2
14	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	17	—	66.2
15	University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM NCI Comprehensive Active Research Program	Active Research Program	9	—	66.2
16	UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR Active Research Program	Active Research Program	12	—	66.2
17	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	10	—	66.2
18	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive Active Research Program	Active Research Program	5	—	66.2
19	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	15	—	66.2
20	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	5	—	66.2
21	Tampa General Hospital Cancer InstituteTampa, FL Active Research Program	Active Research Program	3	—	66.2
22	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive Active Research Program	Active Research Program	6	—	48.2
23	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	3	—	48.2
24	Yale Cancer Center Yale School of MedicineNew Haven, CT NCI Comprehensive Active Research Program	Active Research Program	7	—	48.2
25	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	4	—	48.2
26	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	3	—	48.2
27	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive Active Research Program	Active Research Program	2	—	48.2
28	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive Active Research Program	Active Research Program	4	—	48.2
29	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive Active Research Program	Active Research Program	10	—	48.2
30	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive Active Research Program	Active Research Program	4	—	48.2
31	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive Active Research Program	Active Research Program	5	—	48.2
32	Huntsman Cancer Institute at the University of UtahSalt Lake City, UT NCI Comprehensive Active Research Program	Active Research Program	6	—	48.2
33	Case Comprehensive Cancer CenterCleveland, OH NCI Comprehensive Active Research Program	Active Research Program	5	—	48.2
34	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive Active Research Program	Active Research Program	2	—	48.2
35	Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN NCI Comprehensive Active Research Program	Active Research Program	2	—	48.2
36	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	11	—	48.2
37	UCI Chao Family Comprehensive Cancer CenterOrange, CA NCI Comprehensive Active Research Program	Active Research Program	6	—	48.2
38	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	6	—	48.2
39	Holden Comprehensive Cancer CenterIowa City, IA NCI Comprehensive Active Research Program	Active Research Program	4	—	48.2
40	Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC NCI Comprehensive Active Research Program	Active Research Program	2	—	48.2
41	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	6	—	48.2
42	Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	9	—	48.2
43	Dartmouth Cancer CenterLebanon, NH NCI Comprehensive Active Research Program	Active Research Program	9	—	48.2
44	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	5	—	48.2
45	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical Active Research Program	Active Research Program	7	—	48.2
46	Fox Chase Cancer CenterPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	6	—	48.2
47	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX Active Research Program	Active Research Program	4	—	48.2
48	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	3	—	48.2
49	Penn State Cancer InstituteHershey, PA Active Research Program	Active Research Program	5	—	48.2
50	The Jackson Laboratory Cancer CenterBar Harbor, ME NCI Basic_laboratory Active Research Program	Active Research Program	3	—	48.2
51	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	3	—	48.2
52	UofL James Graham Brown Cancer CenterLouisville, KY Active Research Program	Active Research Program	3	—	48.2
53	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ Active Research Program	Active Research Program	3	—	48.2
54	The University of Vermont Cancer CenterBurlington, VT Active Research Program	Active Research Program	8	—	48.2
55	Northwell Health Cancer InstituteNew York, NY Active Research Program	Active Research Program	3	—	48.2
56	University of Texas Medical Branch Cancer CenterGalveston, TX Active Research Program	Active Research Program	4	—	48.2
57	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	4	—	48.2
58	Murtha Cancer Center at Walter Reed BethesdaBethesda, MD Active Research Program	Active Research Program	1	—	48.2
59	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive		5	—	32.3
60	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive		2	—	32.3
61	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive		7	—	32.3
62	Siteman Cancer CenterSt. Louis, MO NCI Comprehensive		6	—	32.3
63	UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC NCI Comprehensive		5	—	32.3
64	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive		1	—	32.3
65	Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY NCI Comprehensive		2	—	32.3
66	UF Health Cancer InstituteGainesville, FL NCI Clinical		3	—	32.3
67	UC Davis Comprehensive Cancer CenterSacramento, CA NCI Comprehensive		1	—	32.3
68	Cedars-Sinai CancerLos Angeles, CA		2	—	32.3
69	Georgia Cancer Center, Augusta UniversityAugusta, GA		3	—	32.3
70	Upstate Cancer CenterSyracuse, NY		4	—	32.3
71	Princess Margaret Cancer CentreToronto, ON		—	—	32.3
72	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive		—	$827M	—
73	Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA NCI Comprehensive		2	$737M	—
74	University of Michigan Rogel Cancer CenterAnn Arbor, MI NCI Comprehensive		5	$662M	—
75	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive		8	$509M	—
76	Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX NCI Comprehensive		2	$484M	—
77	UMass Memorial Health Cancer CenterWorcester, MA		2	$155M	—
78	Wilmot Cancer Institute, UR MedicineRochester, NY NCI Clinical		3	$153M	—
79	Georgetown Lombardi Comprehensive Cancer CenterWashington, DC NCI Comprehensive		2	$144M	—
80	Ellis Fischel Cancer Center, MU Health CareColumbia, MO		3	$47M	—
81	University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR		2	$34M	—
82	BC CancerVancouver, BC		—	—	—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →