Oropharyngeal Squamous Cell Carcinoma

general

A squamous cell carcinoma arising from the oropharynx. It predominantly affects adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with locally adv

Centers

317

Active Trials

$3.5B

Cancer Funding

Specific Cancer Types(9)

Name	Centers	Active Trials
Recurrent Oropharyngeal Squamous Cell Carcinoma	70	119
Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma	62	62
Stage III Squamous Cell Carcinoma of the Oropharynx	37	34
Refractory Oropharyngeal Squamous Cell Carcinoma	20	20
Stage IV Squamous Cell Carcinoma of the Oropharynx	17	—
Oropharynx Squamous Cell Carcinoma	11	1
Stage II Oropharyngeal Squamous Cell Carcinoma	4	—
Stage I Oropharyngeal Squamous Cell Carcinoma	3	—
Soft Palate Squamous Cell Carcinoma	—	—

Top Centers for Oropharyngeal Squamous Cell Carcinoma(83)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive High-Volume Research Center	High-Volume Research Center	4	$4M	80.8
2	Dartmouth Cancer CenterLebanon, NH NCI Comprehensive High-Volume Research Center	High-Volume Research Center	6	$453K	77.3
3	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive High-Volume Research Center	High-Volume Research Center	7	$451K	76.8
4	Cancer Center at IllinoisUrbana, IL High-Volume Research Center	High-Volume Research Center	8	$427K	76.3
5	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	10	—	69.6
6	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive Active Research Program	Active Research Program	9	—	69.6
7	University of Texas Medical Branch Cancer CenterGalveston, TX Active Research Program	Active Research Program	3	$2M	63.6
8	Siteman Cancer CenterSt. Louis, MO NCI Comprehensive Active Research Program	Active Research Program	5	$1M	63.1
9	Montefiore Einstein Comprehensive Cancer CenterBronx, NY NCI Comprehensive Active Research Program	Active Research Program	5	$1M	62.1
10	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive Active Research Program	Active Research Program	3	—	61.5
11	UPMC Hillman Cancer CenterPittsburgh, PA NCI Comprehensive Active Research Program	Active Research Program	5	—	61.5
12	UC San Diego Moores Cancer CenterLa Jolla, CA NCI Comprehensive Active Research Program	Active Research Program	5	—	61.5
13	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive Active Research Program	Active Research Program	4	—	61.5
14	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	7	—	61.5
15	Moffitt Cancer CenterTampa, FL NCI Comprehensive Active Research Program	Active Research Program	5	—	61.5
16	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	8	—	61.5
17	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	6	—	61.5
18	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	6	—	61.5
19	Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC NCI Comprehensive Active Research Program	Active Research Program	3	—	61.5
20	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	8	—	61.5
21	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	9	—	61.5
22	University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM NCI Comprehensive Active Research Program	Active Research Program	6	—	61.5
23	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	8	—	61.5
24	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive Active Research Program	Active Research Program	3	—	61.5
25	Penn State Cancer InstituteHershey, PA Active Research Program	Active Research Program	5	—	61.5
26	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	4	—	61.5
27	The University of Vermont Cancer CenterBurlington, VT Active Research Program	Active Research Program	5	—	61.5
28	Tampa General Hospital Cancer InstituteTampa, FL Active Research Program	Active Research Program	3	—	61.5
29	UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC NCI Comprehensive Active Research Program	Active Research Program	4	$4M	50.6
30	University of Michigan Rogel Cancer CenterAnn Arbor, MI NCI Comprehensive Active Research Program	Active Research Program	3	$4M	50.1
31	Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	2	$1M	48.1
32	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	6	$683K	47.1
33	University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR Active Research Program	Active Research Program	1	$592K	46.6
34	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive Active Research Program	Active Research Program	5	—	44.8
35	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive Active Research Program	Active Research Program	6	—	44.8
36	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	4	—	44.8
37	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
38	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	8	—	44.8
39	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
40	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive Active Research Program	Active Research Program	6	—	44.8
41	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
42	Huntsman Cancer Institute at the University of UtahSalt Lake City, UT NCI Comprehensive Active Research Program	Active Research Program	4	—	44.8
43	Case Comprehensive Cancer CenterCleveland, OH NCI Comprehensive Active Research Program	Active Research Program	4	—	44.8
44	UC Davis Comprehensive Cancer CenterSacramento, CA NCI Comprehensive Active Research Program	Active Research Program	2	—	44.8
45	Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN NCI Comprehensive Active Research Program	Active Research Program	2	—	44.8
46	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	7	—	44.8
47	UCI Chao Family Comprehensive Cancer CenterOrange, CA NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
48	Cedars-Sinai CancerLos Angeles, CA Active Research Program	Active Research Program	2	—	44.8
49	Wilmot Cancer Institute, UR MedicineRochester, NY NCI Clinical Active Research Program	Active Research Program	3	—	44.8
50	Holden Comprehensive Cancer CenterIowa City, IA NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
51	Georgetown Lombardi Comprehensive Cancer CenterWashington, DC NCI Comprehensive Active Research Program	Active Research Program	2	—	44.8
52	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	5	—	44.8
53	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	3	—	44.8
54	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical Active Research Program	Active Research Program	3	—	44.8
55	UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR Active Research Program	Active Research Program	7	—	44.8
56	Fox Chase Cancer CenterPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	5	—	44.8
57	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	2	—	44.8
58	Upstate Cancer CenterSyracuse, NY Active Research Program	Active Research Program	4	—	44.8
59	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	3	—	44.8
60	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive		2	—	30.4
61	Yale Cancer Center Yale School of MedicineNew Haven, CT NCI Comprehensive		4	—	30.4
62	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive		1	—	30.4
63	UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive		1	—	30.4
64	Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY NCI Comprehensive		1	—	30.4
65	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive		1	—	30.4
66	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX		3	—	30.4
67	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL		2	—	30.4
68	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ		2	—	30.4
69	Georgia Cancer Center, Augusta UniversityAugusta, GA		2	—	30.4
70	Princess Margaret Cancer CentreToronto, ON		—	—	30.4
71	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive		1	$754M	—
72	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive		3	$738M	—
73	Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX NCI Comprehensive		1	$484M	—
74	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive		2	$438M	—
75	OHSU Knight Cancer InstitutePortland, OR NCI Comprehensive		—	$354M	—
76	UF Health Cancer InstituteGainesville, FL NCI Clinical		2	$257M	—
77	Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA NCI Comprehensive		5	$136M	—
78	Stephenson Cancer CenterOklahoma City, OK NCI Clinical		—	$130M	—
79	The Jackson Laboratory Cancer CenterBar Harbor, ME NCI Basic_laboratory		1	$72M	—
80	UofL James Graham Brown Cancer CenterLouisville, KY		2	$59M	—
81	Ellis Fischel Cancer Center, MU Health CareColumbia, MO		2	$47M	—
82	Northwell Health Cancer InstituteNew York, NY		1	$18M	—
83	BC CancerVancouver, BC		—	—	—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →