Marginal Zone Lymphoma

general

A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of ext

Centers

150

Active Trials

$1.9B

Cancer Funding

Specific Cancer Types(6)

Name	Centers	Active Trials
Recurrent Marginal Zone Lymphoma	42	9
Splenic Marginal Zone Lymphoma	34	9
Marginal Zone Lymphoma (MZL)	27	33
Refractory Marginal Zone Lymphoma	23	7
Nodal Marginal Zone B-cell Lymphoma	21	—
Nodal Marginal Zone Lymphoma	20	10

Top Centers for Marginal Zone Lymphoma(74)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive High-Volume Research Center	High-Volume Research Center	8	$2M	89.3
2	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive High-Volume Research Center	High-Volume Research Center	2	$521K	78.0
3	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive High-Volume Research Center	High-Volume Research Center	11	—	71.1
4	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive High-Volume Research Center	High-Volume Research Center	5	—	70.1
5	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	7	—	69.1
6	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	6	—	69.1
7	Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	2	$1M	68.9
8	Moffitt Cancer CenterTampa, FL NCI Comprehensive Active Research Program	Active Research Program	4	—	67.1
9	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	8	—	67.1
10	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	4	—	67.1
11	BC CancerVancouver, BC Active Research Program	Active Research Program	3	—	67.1
12	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	5	—	61.3
13	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	3	—	61.3
14	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive Active Research Program	Active Research Program	3	—	61.3
15	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	2	—	61.3
16	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	6	—	61.3
17	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	5	—	61.3
18	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	5	—	61.3
19	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	2	—	61.3
20	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	2	—	61.3
21	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive Active Research Program	Active Research Program	4	—	61.3
22	Georgia Cancer Center, Augusta UniversityAugusta, GA Active Research Program	Active Research Program	2	—	61.3
23	Upstate Cancer CenterSyracuse, NY Active Research Program	Active Research Program	2	—	61.3
24	University of Texas Medical Branch Cancer CenterGalveston, TX Active Research Program	Active Research Program	2	—	61.3
25	Sandra and Edward Meyer Cancer Center at Weill Cornell MedicineNew York, NY Active Research Program	Active Research Program	—	$3M	54.9
26	Huntsman Cancer Institute at the University of UtahSalt Lake City, UT NCI Comprehensive Active Research Program	Active Research Program	1	$935K	53.4
27	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive Active Research Program	Active Research Program	—	$399K	52.4
28	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive Active Research Program	Active Research Program	4	—	51.2
29	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	51.2
30	OHSU Knight Cancer InstitutePortland, OR NCI Comprehensive Active Research Program	Active Research Program	2	—	51.2
31	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive Active Research Program	Active Research Program	5	—	51.2
32	Wilmot Cancer Institute, UR MedicineRochester, NY NCI Clinical Active Research Program	Active Research Program	1	—	51.2
33	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	3	—	51.2
34	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	2	—	51.2
35	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical Active Research Program	Active Research Program	1	—	51.2
36	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	3	—	51.2
37	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	3	—	51.2
38	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	3	—	51.2
39	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ Active Research Program	Active Research Program	1	—	51.2
40	Legorreta Cancer Center at Brown UniversityProvidence, RI Active Research Program	Active Research Program	1	—	51.2
41	University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR Active Research Program	Active Research Program	1	—	51.2
42	Tampa General Hospital Cancer InstituteTampa, FL Active Research Program	Active Research Program	2	—	51.2
43	Princess Margaret Cancer CentreToronto, ON Active Research Program	Active Research Program	1	—	51.2
44	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive		1	—	36.2
45	UPMC Hillman Cancer CenterPittsburgh, PA NCI Comprehensive		—	—	36.2
46	Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicago, IL NCI Comprehensive		—	—	36.2
47	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive		—	—	36.2
48	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive		—	—	36.2
49	UC San Diego Moores Cancer CenterLa Jolla, CA NCI Comprehensive		—	—	36.2
50	Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX NCI Comprehensive		—	—	36.2
51	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive		—	—	36.2
52	Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY NCI Comprehensive		1	—	36.2
53	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive		6	—	36.2
54	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive		—	—	36.2
55	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive		4	—	36.2
56	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive		—	—	36.2
57	Case Comprehensive Cancer CenterCleveland, OH NCI Comprehensive		—	—	36.2
58	UC Davis Comprehensive Cancer CenterSacramento, CA NCI Comprehensive		—	—	36.2
59	Holden Comprehensive Cancer CenterIowa City, IA NCI Comprehensive		—	—	36.2
60	Georgetown Lombardi Comprehensive Cancer CenterWashington, DC NCI Comprehensive		—	—	36.2
61	Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA NCI Comprehensive		—	—	36.2
62	Dartmouth Cancer CenterLebanon, NH NCI Comprehensive		—	—	36.2
63	UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR		—	—	36.2
64	Fox Chase Cancer CenterPhiladelphia, PA NCI Comprehensive		—	—	36.2
65	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX		—	—	36.2
66	Stony Brook Cancer CenterStony Brook, NY		—	—	36.2
67	Penn State Cancer InstituteHershey, PA		—	—	36.2
68	Livestrong Cancer InstitutesAustin, TX		—	—	36.2
69	Northwell Health Cancer InstituteNew York, NY		—	—	36.2
70	Siteman Cancer CenterSt. Louis, MO NCI Comprehensive		—	$604M	—
71	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive		—	$438M	—
72	Comprehensive Cancer Center St. Jude Children’s Research HospitalMemphis, TN NCI Comprehensive		—	$332M	—
73	UF Health Cancer InstituteGainesville, FL NCI Clinical		—	$257M	—
74	Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN NCI Comprehensive		—	$216M	—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →