Juvenile Myelomonocytic Leukemia

general

A clonal myeloid disorder of childhood previously classified as myelodysplastic/myeloproliferative neoplasm. It is characterized by the presence of monocytic proliferation in peripheral blood, less than 20% blasts in bone marrow and peripheral blood, splenomegaly, and the absence of BCR-ABL1 fusion. Almost all patients carry mutations of the RAS pathway.

Centers

Active Trials

$6M

Cancer Funding

Specific Cancer Types(2)

Name	Centers	Active Trials
Recurrent Juvenile Myelomonocytic Leukemia	5	5
Refractory Juvenile Myelomonocytic Leukemia	5	5

Top Centers for Juvenile Myelomonocytic Leukemia(65)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive High-Volume Research Center	High-Volume Research Center	2	$1M	81.7
2	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive High-Volume Research Center	High-Volume Research Center	6	—	71.6
3	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive High-Volume Research Center	High-Volume Research Center	3	—	70.9
4	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	1	$176K	63.8
5	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
6	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
7	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	4	—	63.6
8	Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
9	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
10	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
11	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	4	—	63.6
12	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	2	—	63.6
13	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
14	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	2	—	63.6
15	Holden Comprehensive Cancer CenterIowa City, IA NCI Comprehensive Active Research Program	Active Research Program	2	—	63.6
16	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	4	—	63.6
17	UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR Active Research Program	Active Research Program	2	—	63.6
18	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	2	—	63.6
19	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX Active Research Program	Active Research Program	2	—	63.6
20	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	2	—	63.6
21	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	4	—	63.6
22	Livestrong Cancer InstitutesAustin, TX Active Research Program	Active Research Program	2	—	63.6
23	Loma Linda University Cancer CenterLoma Linda, CA Active Research Program	Active Research Program	2	—	63.6
24	UCSF Helen Diller Family Comprehensive Cancer CenterSan Francisco, CA NCI Comprehensive Active Research Program	Active Research Program	—	$3M	51.0
25	Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN NCI Comprehensive Active Research Program	Active Research Program	—	$1M	50.0
26	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	—	$788K	49.4
27	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
28	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
29	UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
30	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
31	Yale Cancer Center Yale School of MedicineNew Haven, CT NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
32	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
33	Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
34	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
35	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
36	UF Health Cancer InstituteGainesville, FL NCI Clinical Active Research Program	Active Research Program	1	—	47.3
37	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
38	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	1	—	47.3
39	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	1	—	47.3
40	Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
41	Dartmouth Cancer CenterLebanon, NH NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
42	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
43	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical Active Research Program	Active Research Program	1	—	47.3
44	University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM NCI Comprehensive Active Research Program	Active Research Program	1	—	47.3
45	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	1	—	47.3
46	Penn State Cancer InstituteHershey, PA Active Research Program	Active Research Program	1	—	47.3
47	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	1	—	47.3
48	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ Active Research Program	Active Research Program	1	—	47.3
49	University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR Active Research Program	Active Research Program	1	—	47.3
50	Upstate Cancer CenterSyracuse, NY Active Research Program	Active Research Program	1	—	47.3
51	BC CancerVancouver, BC Active Research Program	Active Research Program	1	—	47.3
52	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	1	—	47.3
53	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive		—	—	32.5
54	UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive		—	—	32.5
55	OHSU Knight Cancer InstitutePortland, OR NCI Comprehensive		—	—	32.5
56	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive		—	—	32.5
57	Comprehensive Cancer Center St. Jude Children’s Research HospitalMemphis, TN NCI Comprehensive		—	—	32.5
58	Case Comprehensive Cancer CenterCleveland, OH NCI Comprehensive		—	—	32.5
59	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive		—	—	32.5
60	Cedars-Sinai CancerLos Angeles, CA		—	—	32.5
61	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive		—	—	32.5
62	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive		—	—	32.5
63	The University of Vermont Cancer CenterBurlington, VT		—	—	32.5
64	Tampa General Hospital Cancer InstituteTampa, FL		—	—	32.5
65	Princess Margaret Cancer CentreToronto, ON		—	—	32.5

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →