Chronic Myeloid Leukemia, BCR-ABL1 Positive

general

A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem

Centers

Active Trials

$9.0B

Cancer Funding

Specific Cancer Types(5)

Name	Centers	Active Trials
Chronic Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive	45	48
Leukemia, Myeloid Chronic	23	12
Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive	5	—
Chronic Myeloid Leukemia, Philadelphia Chromosome Negative, BCR-ABL1 Positive	—	—
Chronic Myeloid Leukemia, Philadelphia Chromosome Positive, BCR-ABL1 Positive	—	—

Top Centers for Chronic Myeloid Leukemia, BCR-ABL1 Positive(60)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive Active Research Program	Active Research Program	3	—	51.7
2	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
3	University of Michigan Rogel Cancer CenterAnn Arbor, MI NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
4	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
5	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	3	—	51.7
6	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
7	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
8	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
9	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
10	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
11	Moffitt Cancer CenterTampa, FL NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
12	Huntsman Cancer Institute at the University of UtahSalt Lake City, UT NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
13	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	2	—	51.7
14	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	2	—	51.7
15	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	3	—	51.7
16	Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
17	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
18	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	2	—	51.7
19	University of New Mexico Comprehensive Cancer CenterAlbuquerque, NM NCI Comprehensive Active Research Program	Active Research Program	1	—	51.7
20	UAMS Winthrop P. Rockefeller Cancer InstituteLittle Rock, AR Active Research Program	Active Research Program	2	—	51.7
21	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	2	—	51.7
22	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	2	—	51.7
23	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	2	—	51.7
24	Penn State Cancer InstituteHershey, PA Active Research Program	Active Research Program	2	—	51.7
25	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	2	—	51.7
26	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	1	—	51.7
27	Upstate Cancer CenterSyracuse, NY Active Research Program	Active Research Program	2	—	51.7
28	Tampa General Hospital Cancer InstituteTampa, FL Active Research Program	Active Research Program	2	—	51.7
29	Princess Margaret Cancer CentreToronto, ON Active Research Program	Active Research Program	3	—	51.7
30	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	2	—	51.7
31	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive		3	$911M	—
32	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive		1	$738M	—
33	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive		1	$655M	—
34	UNC Lineberger Comprehensive Cancer CenterChapel Hill, NC NCI Comprehensive		1	$569M	—
35	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive		1	$509M	—
36	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive		1	$507M	—
37	Dan L Duncan Comprehensive Cancer Center at Baylor College of MedicineHouston, TX NCI Comprehensive		1	$484M	—
38	Duke Cancer InstituteDurham, NC NCI Comprehensive		—	$454M	—
39	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive		1	$438M	—
40	Winship Cancer InstituteAtlanta, GA NCI Comprehensive		2	$375M	—
41	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive		1	$368M	—
42	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive		1	$368M	—
43	OHSU Knight Cancer InstitutePortland, OR NCI Comprehensive		—	$354M	—
44	UF Health Cancer InstituteGainesville, FL NCI Clinical		1	$257M	—
45	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive		2	$223M	—
46	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive		1	$186M	—
47	Cedars-Sinai CancerLos Angeles, CA		1	$179M	—
48	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive		1	$163M	—
49	UMass Memorial Health Cancer CenterWorcester, MA		1	$155M	—
50	Cleveland Clinic Cancer CenterCleveland, OH		2	$150M	—
51	Holden Comprehensive Cancer CenterIowa City, IA NCI Comprehensive		1	$146M	—
52	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical		1	$143M	—
53	Sidney Kimmel Comprehensive Cancer Center at JeffersonPhiladelphia, PA NCI Comprehensive		1	$136M	—
54	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive		1	$123M	—
55	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical		1	$116M	—
56	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive		2	$94M	—
57	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX		1	$83M	—
58	Livestrong Cancer InstitutesAustin, TX		1	$62M	—
59	Georgia Cancer Center, Augusta UniversityAugusta, GA		2	$53M	—
60	University of Puerto Rico Comprehensive Cancer CenterSan Juan, PR		1	$34M	—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →