NUT Carcinoma

general

A rare, highly aggressive and lethal carcinoma that affects children and young adults. It arises from midline epithelial structures, most commonly the head, neck, and mediastinum. It is a poorly differentiated carcinoma and is characterized by mutations and rearrangement of the NUT gene. A balanced translocation t(15;19) is present that results in the creation of a fusion gene involving the NUT gene, most commonly BRD4-NUT fusion gene.

Centers

Active Trials

$335M

Cancer Funding

Specific Cancer Types(1)

Name	Centers	Active Trials
Unresectable NUT Carcinoma	3	6

Top Centers for NUT Carcinoma(18)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive High-Volume Research Center	High-Volume Research Center	4	$464K	87.2
2	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive High-Volume Research Center	High-Volume Research Center	2	—	70.7
3	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
4	Herbert Irving Comprehensive Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
5	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
6	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
7	Masonic Cancer CenterMinneapolis, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
8	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	1	—	50.9
9	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	1	—	50.9
10	Stephenson Cancer CenterOklahoma City, OK NCI Clinical Active Research Program	Active Research Program	1	—	50.9
11	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	1	—	50.9
12	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	3	—	50.9
13	Karmanos Cancer InstituteDetroit, MI NCI Comprehensive Active Research Program	Active Research Program	1	—	50.9
14	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	1	—	50.9
15	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	1	—	50.9
16	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive Active Research Program	Active Research Program	—	$2M	49.6
17	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive		—	—	31.0
18	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive		2	$333M	—

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →