Stage IIIC Rectal Cancer AJCC v8

specific

Stage IIIC includes: (T4a, N2a, M0); (T3-T4a, N2b, M0); (T4b, N1-N2, M0). T3: Tumor invades through the muscularis propria into pericolorectal tissues. T4a: Tumor penetrates to the surface of the visceral peritoneum. T4b: Tumor directly invades or is adherent to other organs or structures. N1: Metastasis in 1-3 regional lymph nodes. N2: Metastasis in four or more regional lymph nodes. N2a: Metastasis in 4-6 regional lymph nodes. N2b: Metastasis in seven or more regional lymph nodes. M0: No dista

Centers

Active Trials

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Cancer Funding

Top Centers for Stage IIIC Rectal Cancer AJCC v8(38)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	OHSU Knight Cancer InstitutePortland, OR NCI Comprehensive High-Volume Research Center	High-Volume Research Center	2	—	72.6
2	University of Illinois Cancer CenterChicago, IL High-Volume Research Center	High-Volume Research Center	2	—	72.6
3	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
4	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
5	UC San Diego Moores Cancer CenterLa Jolla, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
6	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
7	UCLA Jonsson Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
8	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
9	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
10	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
11	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
12	USC Norris Comprehensive Cancer CenterLos Angeles, CA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
13	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
14	Huntsman Cancer Institute at the University of UtahSalt Lake City, UT NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
15	Montefiore Einstein Comprehensive Cancer CenterBronx, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
16	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
17	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	1	—	53.7
18	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
19	Cedars-Sinai CancerLos Angeles, CA Active Research Program	Active Research Program	1	—	53.7
20	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
21	Georgetown Lombardi Comprehensive Cancer CenterWashington, DC NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
22	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	1	—	53.7
23	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
24	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	1	—	53.7
25	University of Hawai‘i Cancer CenterHonolulu, HI NCI Clinical Active Research Program	Active Research Program	1	—	53.7
26	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	1	—	53.7
27	Cancer Center at IllinoisUrbana, IL Active Research Program	Active Research Program	1	—	53.7
28	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	1	—	53.7
29	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	1	—	53.7
30	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ Active Research Program	Active Research Program	1	—	53.7
31	University of Texas Medical Branch Cancer CenterGalveston, TX Active Research Program	Active Research Program	1	—	53.7
32	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	1	—	53.7
33	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive		—	—	32.4
34	Siteman Cancer CenterSt. Louis, MO NCI Comprehensive		—	—	32.4
35	Yale Cancer Center Yale School of MedicineNew Haven, CT NCI Comprehensive		—	—	32.4
36	Vanderbilt-Ingram Cancer CenterNashville, TN NCI Comprehensive		—	—	32.4
37	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive		—	—	32.4
38	Laura and Isaac Perlmutter Cancer Center at NYU Langone HealthNew York, NY NCI Comprehensive		—	—	32.4

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →