Brain Tumor, Primary

specific

An aggressive malignant embryonal neoplasm arising from the central nervous system. It is composed of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. Mutations of the SMARCB1 gene or very rarely SMARCA4 (BRG1) gene are present. The vast majority of cases occur in childhood. Symptoms include lethargy, vomiting, cranial nerve palsy, headache, and hemiplegia.

Centers

Active Trials

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Cancer Funding

Top Centers for Brain Tumor, Primary(18)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Winship Cancer InstituteAtlanta, GA NCI Comprehensive Active Research Program	Active Research Program	1	—	56.5
2	University of Colorado Cancer CenterAurora, CO NCI Comprehensive Active Research Program	Active Research Program	1	—	56.5
3	University of Virginia Cancer CenterCharlottesville, VA NCI Comprehensive Active Research Program	Active Research Program	1	—	56.5
4	Sylvester Comprehensive Cancer CenterMiami, FL NCI Clinical Active Research Program	Active Research Program	1	—	56.5
5	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	1	—	56.5
6	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	1	—	56.5
7	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	1	—	56.5
8	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	1	—	56.5
9	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	1	—	56.5
10	Houston Methodist Dr. Mary and Ron Neal Cancer CenterHouston, TX Active Research Program	Active Research Program	1	—	56.5
11	Penn State Cancer InstituteHershey, PA Active Research Program	Active Research Program	1	—	56.5
12	University of Cincinnati Cancer CenterCincinnati, OH Active Research Program	Active Research Program	1	—	56.5
13	Upstate Cancer CenterSyracuse, NY Active Research Program	Active Research Program	1	—	56.5
14	Tampa General Hospital Cancer InstituteTampa, FL Active Research Program	Active Research Program	1	—	56.5
15	Louisiana Cancer Research CenterNew Orleans, LA Active Research Program	Active Research Program	1	—	56.5
16	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive		—	—	34.0
17	Stanford Cancer InstitutePalo Alto, CA NCI Comprehensive		—	—	34.0
18	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive		—	—	34.0

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →