VEXAS Syndrome

specific

An X-linked inherited condition caused by somatic mutation(s) in the UBA1 gene, encoding ubiquitin-like modifier-activating enzyme 1. It is characterized by the adult onset of rheumatologic symptoms in males, including recurrent fevers, pulmonary and dermatologic inflammatory manifestations, vasculitis, arthralgias, facial chondritis and hematologic abnormalities.

Centers

Active Trials

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Cancer Funding

Top Centers for VEXAS Syndrome(8)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive Active Research Program	Active Research Program	1	—	56.2
2	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive Active Research Program	Active Research Program	1	—	56.2
3	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	1	—	56.2
4	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	1	—	56.2
5	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	1	—	56.2
6	Boston University Cancer CenterBoston, MA Active Research Program	Active Research Program	1	—	56.2
7	BC CancerVancouver, BC Active Research Program	Active Research Program	1	—	56.2
8	Princess Margaret Cancer CentreToronto, ON Active Research Program	Active Research Program	1	—	56.2

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →