Myeloid Leukemia, Acute

specific

Two major types of genetic events are crucial for the molecular pathogenesis of acute myeloid leukemias (AML): activating mutations of signal transduction intermediates and alterations in myeloid transcription factors governing hematopoietic differentiation. Both aberrant and constitutive activation of signal transduction molecules are found in about 50% of primary AML bone marrow samples, and seem to contribute to the increased proliferation and apoptosis resistance. The most common of these ac

Centers

Active Trials

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Cancer Funding

Top Centers for Myeloid Leukemia, Acute(19)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Memorial Sloan Kettering Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
2	Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
3	Fred Hutch Cancer CenterSeattle, WA NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
4	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
5	Yale Cancer Center Yale School of MedicineNew Haven, CT NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
6	The University of Texas MD Anderson Cancer CenterHouston, TX NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
7	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
8	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
9	The University of Arizona Cancer CenterTucson, AZ NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
10	Medical College of Wisconsin Cancer CenterMilwaukee, WI Active Research Program	Active Research Program	1	—	52.6
11	Cleveland Clinic Cancer CenterCleveland, OH Active Research Program	Active Research Program	1	—	52.6
12	Atrium Health Wake Forest Baptist Comprehensive Cancer CenterWinston-Salem, NC NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
13	Fred & Pamela Buffett Cancer CenterOmaha, NE NCI Clinical Active Research Program	Active Research Program	1	—	52.6
14	The University of Kansas Cancer CenterKansas City, KS NCI Comprehensive Active Research Program	Active Research Program	1	—	52.6
15	University of Illinois Cancer CenterChicago, IL Active Research Program	Active Research Program	1	—	52.6
16	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	1	—	52.6
17	Mayo Clinic Comprehensive Cancer Center, FloridaJacksonville, FL Active Research Program	Active Research Program	1	—	52.6
18	Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ Active Research Program	Active Research Program	1	—	52.6
19	Princess Margaret Cancer CentreToronto, ON Active Research Program	Active Research Program	1	—	52.6

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →