Attenuated Familial Adenomatous Polyposis
specificA rare genetic syndrome with an autosomal dominant pattern of inheritance. It was formerly called hereditary flat adenoma syndrome (HFAS) but is now recognized as an attenuated variant of familial adenomatous polyposis (FAP). It is most commonly associated with mutations in the APC gene specifically: exons 1-5, exon 9 and in the distal 3' terminus. Clinical presentation occurs in the middle decades and is characterized by the proximal development of multiple (but less than 100), non-polypoid col
7
Centers
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Active Trials
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Cancer Funding
Top Centers for Attenuated Familial Adenomatous Polyposis(7)
Ranked by research excellence score (trials · grants · publications). Methodology →
| # | Center | Score |
|---|---|---|
| 1 | Dana-Farber Cancer InstituteBoston, MA NCI Comprehensive | 57.1 |
| 2 | University of Michigan Rogel Cancer CenterAnn Arbor, MI NCI Comprehensive | 57.1 |
| 3 | Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive | 57.1 |
| 4 | Cleveland Clinic Cancer CenterCleveland, OH | 57.1 |
| 5 | Boston University Cancer CenterBoston, MA | 57.1 |
| 6 | Mayo Clinic Comprehensive Cancer Center, ArizonaScottsdale, AZ | 57.1 |
| 7 | 57.1 |
Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →