First-Line Therapy

specific

Initial treatment used to reduce a cancer. First-line therapy is followed by other treatments, such as chemotherapy, radiation therapy, and hormone therapy to get rid of cancer that remains.

Centers

Active Trials

$32M

Cancer Funding

Top Centers for First-Line Therapy(17)

Ranked by research excellence score (trials · grants · publications). Methodology →

#	Center	Research Tier	Active Trials	Cancer Funding	Score
1	Indiana University Melvin and Bren Simon Comprehensive Cancer CenterIndianapolis, IN NCI Comprehensive Active Research Program	Active Research Program	—	$6M	69.4
2	Roswell Park Comprehensive Cancer CenterBuffalo, NY NCI Comprehensive Active Research Program	Active Research Program	—	$3M	67.4
3	Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, PA NCI Comprehensive Active Research Program	Active Research Program	—	$3M	65.3
4	Mount Sinai Tisch Cancer CenterNew York, NY NCI Comprehensive Active Research Program	Active Research Program	—	$3M	63.2
5	Mayo Clinic Comprehensive Cancer CenterRochester, MN NCI Comprehensive Active Research Program	Active Research Program	—	$3M	61.2
6	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins UniversityBaltimore, MD NCI Comprehensive Active Research Program	Active Research Program	—	$2M	59.1
7	Moffitt Cancer CenterTampa, FL NCI Comprehensive Active Research Program	Active Research Program	—	$2M	57.1
8	City of Hope Comprehensive Cancer CenterDuarte, CA NCI Comprehensive Active Research Program	Active Research Program	—	$2M	55.0
9	The Ohio State University Comprehensive Cancer Center - James Cancer Hospital & Solove Research InstituteColumbus, OH NCI Comprehensive Active Research Program	Active Research Program	—	$2M	52.9
10	Simmons Comprehensive Cancer Center UT Southwestern Medical CenterDallas, TX NCI Comprehensive Active Research Program	Active Research Program	—	$1M	50.9
11	University of Wisconsin Carbone Cancer CenterMadison, WI NCI Comprehensive Active Research Program	Active Research Program	—	$1M	48.8
12	Rutgers Cancer InstituteNew Brunswick, NJ NCI Comprehensive Active Research Program	Active Research Program	—	$1M	46.8
13	VCU Massey Comprehensive Cancer CenterRichmond, VA NCI Comprehensive Active Research Program	Active Research Program	—	$788K	44.7
14	University of Michigan Rogel Cancer CenterAnn Arbor, MI NCI Comprehensive Active Research Program	Active Research Program	—	$669K	42.6
15	The University of Chicago Medicine Comprehensive Cancer CenterChicago, IL NCI Comprehensive Active Research Program	Active Research Program	—	$430K	40.6
16	Stony Brook Cancer CenterStony Brook, NY Active Research Program	Active Research Program	—	$175K	38.5
17	Duke Cancer InstituteDurham, NC NCI Comprehensive Active Research Program	Active Research Program	—	$43K	36.5

Research tier badges reflect trial volume, NIH grant funding, and publication impact — not clinical outcomes or patient satisfaction. Learn about our methodology →