Childhood Acute Megakaryoblastic Leukemia
specificA subtype of acute myeloid leukemia involving the megakaryocytic line. The majority of the cases are associated with t(1;22)(p13;q13). The following recurrent genetic abnormalities have been reported with pediatric AMKL: NUP98/JARID1A, RBM15/MKL, and CBFA2T3/GLIS2. GATA1 mutations are not observed in non-Trisomy 21 (Down syndrome) children with AMKL.
Top Centers for Childhood Acute Megakaryoblastic Leukemia
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